产品货号：
Z23761
中文名称：
PMVK抗体
英文名称：
Anti-PMVK Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PMVK Antibody |
| 指标别名 | hPMK;HUMPMKI;phosphomevalonate kinase;PMK;PMKA;PMKASE;PMKI;PMVK |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC |
| 基因名称 | PMVK |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence in the middle region of human PMVK(135-151aa EQSRQQRGWVFTPGVDD),identical to the related mouse sequence,and different from the related rat sequence by one amino acid. |
| 实际分子量 | 23KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | PMVK(phosphomevalonate kinase) is a cytosolic enzyme that catalyzes the conversion of mevalonate-5-phosphate to mevalonate-5-diphosphate.It is mapped to chromosome 1p13-1q22-23 and spans more than 8.4kb in the human genome.PMVK is a peroxisomal protein which requires the C-terminal peroxisomal targeting signal,Ser-Arg-Leu,for localization to the organelle.It was expressed highly in heart,liver,skeletal muscle,kidney and pancreas and slightly lower in brain,placenta,and lung.And PMKase gene expression is subject to regulation by sterol at the level of transcription.It is a single copy gene covering less than 15kb in the human genome.The human PMKase amino acid sequence contains a consensus peroxisomal targeting sequence(PTS-1),Ser-Arg-Leu,at the C terminus of the protein. |
| Uniprot ID | Q15126 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | phosphomevalonate kinase |
| 蛋白名全称 | Phosphomevalonate kinase(PMKase/hPMK) |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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